hypusine residue; Lys-Bu-NH2

Function

• posttranslational modification only found in mature eIF-5A
• hypusine is derived from Lys by the post-translational addition of a butylamino group (from spermidine) to the epsilon-amino group of Lys

More general terms

• variant amino acid residue

Additional terms

• deoxyhypusine hydroxylase; hDOHH; deoxyhypusine dioxygenase; deoxyhypusine monooxygenase; HEAT-like repeat-containing protein 1 (DOHH, HLRC1)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=65396
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=128065
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=125584