deoxyhypusine hydroxylase; hDOHH; deoxyhypusine dioxygenase; deoxyhypusine monooxygenase; HEAT-like repeat-containing protein 1 (DOHH, HLRC1)

Function

• hypusine synthesis, 2nd step
• catalyzes hydroxylation of the 6-N-(4-aminobutyl)-L-lysine intermediate to form hypusine

Cofactor:

• binds 2 Fe+2 per subunit

More general terms

• hydroxylase; monooxygenase
• metalloprotein

Additional terms

• hypusine residue; Lys-Bu-NH2

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=83475
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:83475
• OMIM: https://mirror.omim.org/entry/611262
• UniProt: http://www.uniprot.org/uniprot/Q9BU89.html