macroamylase in serum/plasma

Clinical significance

• protein bound amylase
• due to its larger size, macroamylase may not be cleared as fast as the smaller non-protein bound amylase, thus levels may be elevated in the absence of pathology

Increases

• macroamylasemia

Methods

• direct identification in serum requires ultracentrifugation or chromatography
• indirect methods:
  • selective precipitation of macroamylase in a polyethylene glycol solution
  • temperature sensitive amylase assay (dissociation of amylase from complexed proteins)

More general terms

• macroamylase in body fluid

Additional terms

• amylase
• macroamylase
• macroamylasemia

Component of

• macroamylase/amylase in serum/plasma