drug interaction(s) of aspirin, clopidogrel & warfarin
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Drug interactions
- relative risk of hemorrage relative to monotherapy with warfarin
- aspirin 0.96
- clopidogrel 1.33
- clopidogrel + aspirin 1.47
- warfarin + aspirin 1.75
- ref[2] gives a much higher relative risk (7.3)
- warfarin + clopidogrel 3.57
- warfarin + clopidogrel + aspirin 4.03
More general terms
References
- ↑ Hansen ML et al Risk of Bleeding With Single, Dual, or Triple Therapy With Warfarin, Aspirin, and Clopidogrel in Patients With Atrial Fibrillation Arch Intern Med. 2010;170(16):1433-1441. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/20837828 <Internet> http://archinte.ama-assn.org/cgi/content/short/170/16/1433
- ↑ 2.0 2.1 Hamon M et al. Incidence, source, determinants, and prognostic impact of major bleeding in outpatients with stable coronary artery disease. J Am Coll Cardiol 2014 Oct 7; 64:1430. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25277612
Dauerman HL. Reconsidering the necessity of aspirin in stable coronary artery disease. J Am Coll Cardiol 2014 Oct 7; 64:1437 PMID: https://www.ncbi.nlm.nih.gov/pubmed/25277613