chromosomal translocation t(1;14)(p22;q32) (MALT lymphoma)

Introduction

- chromosomal translocation t(1;14)(p22;q32) involving BCL10 with IgH is recurrent in low-grade MALT lymphoma; although the BCL10/IgH translocation leaves the coding region of BCL10 intact, frequent BCL10 mutations may occur via the Ig somatic hypermutation mechanism resulting in nucleotide transitions

More general terms

• chromosomal translocation

Additional terms

• extranodal marginal zone B-cell lymphoma; low grade B-cell lymphoma of MALT [mucosa associated lymphoid tissue] type, MALToma