palmoplantar keratoderma striate type 2; keratosis palmoplantaris striata 2 (SPPK2)

Genetics

• associated with defects in DSP

Clinical manifestations

• skin thickening in the palms (linear pattern) & the soles (island-like pattern) & flexor aspect of the fingers
• abnormalities of the nails, teeth & hair are rarely present

More general terms

• palmoplantar keratoderma striate

Database

• OMIM: https://mirror.omim.org/entry/125647