chromosomal translocation t(7;10)(q32;q11)

Introduction

Chromosomal translocation t(7;10)(q32;q11) involving RET with TIF1/TRIM24 generates the TIF1/RET (PTC6) oncogene. Associated with thyroid papillary carcinoma.

More general terms

• chromosomal translocation

Additional terms

• proto-oncogene tyrosine-protein kinase receptor ret; C-ret; (RET, CDHF12)
• transcription intermediary factor 1-alpha; TIF1-alpha; RING finger protein 82; tripartite motif-containing protein 24 (TRIM24, RNF82, TIF1, TIF1A)