tesofensine

Indications

• pharmaceutical aid for weight reduction

Dosage

• 0.25-1.0 mg PO QD

Adverse effects

• most common side effects are gastrointestinal & dose-related
  • dry mouth
  • nausea
  • constipation, hard stools
  • diarrhea
  • insomnia
• increased blood pressure 1.0 mg
• increased heart rate (7.4 beats per min, 0.5 mg)

Mechanism of action

• inhibits presynaptic uptake of noradrenaline, dopamine, & serotonin,

More general terms

• anorexiant (appetite suppressant)