drug interaction(s) of tamoxifen with paroxetine
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Drug interactions
- tamoxifen is metabolized by cyt P450 2D6 to an active metabolite
- paroxetine (Paxil) inhibits cyt P450 2D6. thus co-admnistration of paroxetine & tamoxifen may result low levels of active tamoxifen metabolite
More general terms
References
- ↑ Prescriber's Letter 11(1):3 2004 Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=200124&pb=PRL (subscription needed) http://www.prescribersletter.com