polyglutamine expansion disorder

Introduction

Genetic disorders associated with CAG trinucleotide repeat expansions.

More general terms

• trinucleotide repeat expansion disease
• neurodegenerative disease

More specific terms

• dentatorubral-pallidoluysian atrophy (DRPLA)
• Huntington disease-like type 2
• Huntington's disease; Huntington's chorea (progressive hereditary chorea)
• olivopontocerebellar atrophy type 1 (Menzel type); spinocerebellar ataxia type 1 (SCA-1)
• spinocerebellar ataxia type 17 (SCA-17)
• spinocerebellar ataxia type 2 (SCA-2); olivopontocerebellar atrophy, Holguin type
• spinocerebellar ataxia type 3 (SCA-3); Machado-Joseph disease; Azorean disease
• spinocerebellar ataxia type 6 (SCA-6)
• spinocerebellar ataxia type 7 (SCA-7); olivopontocerebellar atrophy type 3 (retinal degeneration)
• X-linked bulbospinal muscular atrophy (Kennedy's disease)