Merkel cell virus

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Introduction

icosahedral dsDNA virus

lacks a lipoorotein envelope

Size: 5387 base pairs

Epidemiology

  • commonly found in normal human skin

Pathology

Laboratory

More general terms

Additional terms

References

  1. Feng H et al, Clonal integration of a polyoma virus in human Merkel cell carcinoma. Science 2008, Jan 17 ePub PMID: https://www.ncbi.nlm.nih.gov/pubmed/18202256
  2. Touze A et al High levels of antibodies against Merkel cell polyomavirus identify a subset of patients with Merkel cell carcinoma with better clinical outcome. J Clin Oncol 2011 Apr 20; 29:1612. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21422439
    Paulson KG et al. Transcriptome-wide studies of Merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J Clin Oncol 2011 Apr 20; 29:1539. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21422430