receptor-type tyrosine-protein phosphatase gamma; protein-tyrosine phosphatase gamma; R-PTP-gamma (PTPRG, PTPG)

Function

• possesses tyrosine phosphatase activity
• monomer: active form; homodimer: inactive form (probable)

protein tyrosine phosphate + H2O = protein tyrosine + phosphate

Structure

• belongs to the protein-tyrosine phosphatase family receptor class 5 subfamily
• contains 1 alpha-carbonic anhydrase domain
• contains 1 fibronectin F3 module
• contains 2 tyrosine-protein phosphatase domains

Compartment

• membrane; single-pass type 1 membrane protein (probable)

Alternative splicing

named isoforms=2

Expression

found in a variety of tissues

More general terms

• tyrosine phosphatase, receptor type
• plasma membrane protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5793
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5793
• OMIM: https://mirror.omim.org/entry/176886
• UniProt: http://www.uniprot.org/uniprot/P23470.html