glitazar
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Mechanism of action
- so-called 2 in 1 drugs.
- improve blood glucose similar to thiazolidinediones
- improve lipid profile similar to fibrates
- activates both PPAR-alpha & PPAR-gamma
- activation of PPAR-gamma decreases plasma glucose & free fatty acid concentrations
- activation of PPAR-alpha receptors decreases plasma triglyceride & increases plasma HDL cholesterol
More general terms
More specific terms
References
- ↑ Prescriber's Letter 12(9): 2005 Diabetes Drugs on the Horizon: Investigational Drug: Muraglitazar (Pargluva) Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=210905&pb=PRL (subscription needed) http://www.prescribersletter.com