streptococcal pyrogenic exotoxin A
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Introduction
Streptococcal M protein types 1 & 3 produce streptococcal pyrogenic exotoxin A, B &/or C.
Epidemiology
- a new emm1 strain (M1UK) of Streptococcus pyogenes associated with an outbreak of scarlet fever in 2014-2016 in the UK produces 9X more streptococcal pyrogenic exotoxin A than other emm1 strains[2]
More general terms
Additional terms
- group A beta-hemolytic streptococcus
- streptococcal pyrogenic exotoxin B
- streptococcal pyrogenic exotoxin C
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- ↑ 2.0 2.1 Lynskey NN, Jauneikaite E, Li HK et al Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population- based molecular epidemiological study. Lancet Infectious Diseases. Sept 10, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31519541 Free Article https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30446-3/fulltext
Brouwer S, Lacey JA, You Y, Davies MR, Walker MJ. Scarlet fever changes its spots. Lancet Infectious Diseases. Sept 10, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31519542 Free Article https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30494-3/fulltext