methylcobalamin (vitamin B12)
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Introduction
Methylcobalamin the cofactor of methionine synthase (homocysteine methyltransferase, a methylcobalamin & N5-methyltetrahydrofolate- dependent enzyme.
In connection with 5,10 methylenetetrahydrofolate reductase activity which generates 5-methyltetrahydrofolate, methionine synthase regulates methionine synthesis & tetrahydrofolate generation. The availability of tetrahydrofolate is critical to DNA & RNA generation.
More general terms
Additional terms
- intrinsic factor; gastric intrinsic factor; IF; INF (GIF, IFMH)
- methionine synthase; 5-methyltetrahydrofolate:homocysteine methyltransferase; vitamin-B12 dependent methionine synthase; tetrahydropteroyl-glutamate methyltransferase; MS (MTR)
- Schilling test
- transcobalamin
- vitamin B12 deficiency
- vitamin B12 in serum/plasma
Component of
- betaine/folic acid/methylcobalamin/pyridoxine
- ascorbate/biotin/ferrous fumarate/folic acid/methylcobalamin/nicotinamide/pantothenate/pyridoxine/riboflavin/thiamine
- methylcobalamin/pyridoxal phosphate
- folic acid/methylcobalamin/pyridoxine
- ascorbate/biotin/ferrous fumarate/folic acid/iron/methylcobalamin/nicotinamide/pantothenate/pyridoxine/riboflavin/thiamine
- acetylcysteine/methylcobalamin
- acetylcysteine/folic acid/methylcobalamin