leukotriene D

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Introduction

Together with leukotriene-C & E = SRS-A (slow-reacting substance of anaphylaxis). Promotes smooth muscle contraction of pulmonary airways, trachea & intestines, & increases permeability of microvasculature. [For molecular structure, see specific subtype in arachidonate or eicosapentaenoate cascade.]

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References

  1. Textbook of Biochemistry with Clinical Correlations, 3rd ed., TM Devlin (ed), Wiley-Liss, NY 1992 pg 469