1,4-dithiothreitol; 1,4-dimercapato-2,3-butanediol (DTT, Cleland's reagent)
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Introduction
Used in vitro to reduce protein disulfides to thiols (cysteine residues). Product of dithiothreitol reduction of protein disulfides is a 6 membered ring, thus driving the reaction in the direction of protein thiols.
More general terms
References
- ↑ Calbiochem Technical Bulletin http://www.emdbiosciences.com/product/CB0121
Database
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=161958
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=272126
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=31362
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=3563
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=170245
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=838120
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=836372