monoethylglycinexylidide (MEGX, Ethylglycylxylidide)

Introduction

Alias MEGX.

Hepatic metabolites of lidocaine include MEGX & glycinexylidide (GX). Renal failure leads to accumulation of MEGX & GX which have little pharmacologic activity, but can produce significant neurotoxicity.

More general terms

• amine
• carboxylate
• pharmacologic metabolite

Additional terms

• lidocaine (Xylocaine)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=24415