tautomycin
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Introduction
From Streptomyces spiroverticillatus. Inhibits PP1 (IC50=1nM), PP2A (IC50=10nM), smooth muscle endogenous phosphatase (IC50=6nM). Does not inhibit PP2C, myosin light chain kinase.
More general terms
References
- ↑ Calbiochem flyer: Suganuma et al Toxicon 30:873 1992 Gong et al J Biol Chem 267:14662 1992 MacKintosh & Klumpp FEBS Lett 277:137 1990 Magae et al J Antibiot 42:1290 1989