nitrous oxide; laughing gas (N2O)
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Introduction
Non-flammable, nearly odorless gas.
Indications
- anesthesia
- symptoms of depression
Pharmacokinetics
elimination via lung
Adverse effects
- chronic abuse may lead to functional vitamin B12 deficiency due to inactivation[3]
Laboratory
- nitrous oxide in blood
- specimen: whole blood
- methods: GLC, GC-MS
- other labs with Loincs
Mechanism of action
good anesthetic at safe concentrations
More general terms
Additional terms
Component of
References
- ↑ Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995
- ↑ Clinical Guide to Laboratory Tests, NW Tietz (ed) 3rd ed, WB Saunders, Philadelpha 1995
- ↑ 3.0 3.1 Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018
- ↑ 4.0 4.1 Kneisel K Neuropathy After Recreational Use of Laughing Gas. Clinicians should be aware of adverse effects of this increasingly popular drug. MedPage Today August 23, 2021 https://www.medpagetoday.com/casestudies/neurology/94170
Pedersen OB, Hvas AM, Grove EL A 19-year-old man with a history of recreational inhalation of nitrous oxide with severe peripheral neuropathy and central pulmonary embolism. Am J Case Rep 2021. Aug 11;22:e931936 PMID: https://pubmed.ncbi.nlm.nih.gov/34376630 https://www.amjcaserep.com/abstract/index/idArt/931936 - ↑ Gill K, de Cates AN, Wiseman C et al Nitrous oxide for the treatment of depression: a systematic review and meta-analysis. EBioMedicine. 2025 Nov 30:106023. PMID: https://pubmed.ncbi.nlm.nih.gov/41326290 Free article. https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00467-0/fulltext