frovatriptan (Frova)

Introduction

Tradename: Frova. Scheduled for release in 2002.

Indications

migraine headache

Dosage

• 2.5 mg; may repeat after 2 hours
• maximum: 7.5 mg QD

Tabs: 2.5 mg

Pharmacokinetics

• slow onset of action, long duration
• elimination 1/2 life of 26 hours

Mechanism of action

• serotonin receptor agonist

Notes

Manufacturer: Elan

More general terms

• serotonin agonist (5-HT receptor agonist, triptan)
• heterocyclic compound, 2 rings
• amine

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=77992
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5284561
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=152943
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=152944