cevimeline (Evoxac, Saligren)

Introduction

Tradename: Evoxac.

Indications

dry mouth due to Sjogren's syndrome

Dosage

30 mg PO TID

Tabs: 30 mg.

Adverse effects

• cholinergic effects
  • sweating
  • nausea
  • rhinitis
  • diarrhea
  • may impair vision especially at night

Mechanism of action

stimulates salivary secretion

More general terms

• parasympathomimetic (cholinergic agent)

Additional terms

• Sjogren's syndrome (autoimmune epitheliitis)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=83927
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5284532
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=83898
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=123603
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2684