Demons-Meigs syndrome

Introduction

benign ovarian disease associated with a pleural effusion

Pathology

• ovarian fibroma* (most common)
• fibrothecoma
• ascites
• pleural effusion

* only 1-2% of patients with ovarian fibroma present with Demons-Meigs syndrome

Clinical manifestations

• abnormal uterine bleeding (case report)

Laboratory

• serum CA125 often elevated

Differential diagnosis

• ovarian cancer

Management

• surgical resection (TAH-BSO) of the ovarian fibroma results in permanent resolution of the pleural effusion

More general terms

• syndrome