Modification of diet in Renal Disease (MDRD) Study equation

Introduction

Equation used in the MDRD study to estimate GFR

Principle

GFR = serum creatinine [exp 1.154] x age [exp -2.03] x Kf* ,

* Kf = 0.742 if female, 1.212 if black

Notes

• most useful when eGFR is 15-60 mL/min/1.73 m2
• underestimates GFR when GFR > 60 mL/min/1.73 m2
• less accurate is populations with normal or near normal GFR, extremes of age or weight, amputees, pregnancy, cirrhosis

Additional terms

• Modification of diet in Renal Disease (MDRD) Study

Components

• creatinine in serum/plasma