norepinephrine metabolism

Biochemistry

• norepinephrine metabolism 1
  • enzyme: monoamine oxidase
  • substrate: norepinephrine + O2 + H2O
  • product: DOMA + H2O2 + NH3
• norepinephrine metabolism 2
  • enzyme: catechol-O-methyltransferase
  • substrate: norepinephrine + SAM
  • product: normetanephrine + S-adenosylhomocysteine
• norepinephrine metabolism 3
  • enzyme: catechol-O-methyltransferase
  • substrate: DOMA + SAM
  • product: VMA S-adenosylhomocysteine
• norepinephrine metabolism 4
  • enzyme: monoamine oxidase
  • substrate: normetanephrine + O2 + H2O
  • product: VMA + MHPG + H2O2 + NH3

* see figure

More general terms

• catecholamine metabolism

Additional terms

• norepinephrine; noradrenaline (Levophed)