protein synthesis termination

Biochemistry

* see figure 1

• protein synthesis 17
  • substrate: eukaryotic release factor + 80S-termination complex :p-site transfer RNA :amino-acyl peptide :product 80S-elongation complex (GDP, RNA-binding motif - UAG) :a-site eukaryotic release factor (peptidyl transferase) :p-site transfer RNA :amino-acyl protein

* see figure 2

• protein synthesis 18
  • enzyme: peptidyl transferase
  • substrate: 80S-termination complex :a-site eukaryotic release factor (peptidyl transferase, GDP, RNA-binding motif - UAG) :p-site transfer RNA :amino-acyl protein :product 80S-termination complex :a-site eukaryotic release factor (peptidyl transferase, GTP, RNA-binding motif - UAG) :p-site transfer RNA :amino-acyl unbound + protein

* see figure 3

• protein synthesis 19
  • substrate: 80S-termination complex :a-site eukaryotic release factor (peptidyl transferase, GTP, RNA-binding motif - UAG) :p-site transfer RNA :amino-acyl unbound :product 60S-ribosomal subunit + 40S-ribosomal subunit) + messenger RNA + CAP-binding protein + + transfer RNA :amino-acyl unbound + eukaryotic release factor (GDP) + H2PO4-

More general terms

• protein synthesis