lipofuscin

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Introduction

Yellow-brown, finely granular intracytoplasmic pigment, particularly prominent in liver & heart of aging patients. Represents indigestible residue of autophagocytic vesicles. Composed of polymers of lipids & phospholipids complexed with protein.

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References

  1. Cotran et al, Robbins Pathologic Basis of Disease, W.B. Saunders Co, Philadelphia, PA 1989 pg 24
  2. Harman, Lipofuscin & Ceroid Pigments, EA Porta (ed), Plenum Press, NY, 1990, pg 3