Morquio disease; mucopolysaccharidosis-4; eccentro-osteochondrodysplasia; MPS4
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Pathology
- aortic valvular lesions (aortic incompetence)
- severe skeletal deformities (vertebrate & epiphyses)
Clinical manifestations
- severe skeletal deformities
- dwarfism
- thoracolumbar gibbus
- kyphoscoliosis
- cloudy cornea
- normal intelligence
- wide range of severity
Prognosis: life expectancy: 3rd to 6th decade
More general terms
More specific terms
- Morquio disease type-A; mucopolysaccharidosis 4a; MPS4a
- Morquio disease type-B; mucopolysaccharidosis 4b; Morquio syndrome B; MPS4b
References
- ↑ Textbook of Biochemistry with Clinical Correlations, 3rd ed., TM Devlin (ed), Wiley-Liss, NY 1992 pg 383
- ↑ Cotran et al Robbins Pathologic Basis of Disease, W.B. Saunders Co, Philadelphia, PA 1989 pg 150
- ↑ Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1038