frontotemporal dementia with parkinsonism (FTDP-17); multiple system tauopathy with presenile dementia (MSTD)

Introduction

Associated mutations in tau tended to reduce ability of tau to bind microtubules & promote microtubule assembly.

More general terms

• frontotemporal dementia
• parkinson plus syndrome
• genetic disease of the central nervous system

Additional terms

• disinhibition-dementia-parkinsonism-amyotrophy complex (DDPAC)
• parkinsonism

Database

• OMIM: https://mirror.omim.org/entry/600274
• OMIM: https://mirror.omim.org/entry/157140