death effector domain (DED)

Introduction

alpha helical structure

Typically associates with other DED-containing proteins, forming either dimers or trimer

DED containing proteins include:

• FADD/MORT1
• Caspase-8
  • Caspase-10
• v-FLIP, FLICE
• c-FLIP
• PEA15

More general terms

• peptide motif
• domain