PEST region
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Introduction
Motif common to most calpain sensitive proteins. Contains proline, glutamate, aspartate, serine & threonine residues. Site for serine/threonine kinase & Ca+2-binding.
More general terms
References
- ↑ Choi JY et al Molecular clonining and expression of a complementary DNA for inositol 1,4,5-triphosphate 3-kinase Science 248:64 1990 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2157285
- ↑ Wang KK et al Calmodulin-binding proteins as calpain substrates. Biochem J 262:693 1989 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2556106
- ↑ Rogers S et al, Amino acids common to rapidly degraded proteins: The PEST hypothesis Science 234:364 1986 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2876518