Diego blood group locus

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Genetics

SLC4A1 is responsible for the Diego blood group system
- the molecular basis of the Di(a)=Di1/Di(b)/Di2 blood group antigens is a single variation in position 854
  - Leu-854 corresponds to Di(a) & Pro-854 to Di(b)
the molecular basis of the Wr(a)=Di3/Wr(b)/Di4 blood group antigens is a single variation in position 658
- Lys-658 corresponds to Wr(a) & Glu-658 to Wr(b)
the blood group antigens Wd(a)=Di5 (Waldner-type) has Met-557
- Rb(a)=Di6 has Leu-548 & WARR=Di7 has Ile-552