tribbles homolog 1 (TRB-1, SKIP1, G-protein-coupled receptor-induced protein 2, GIG-2, TRIB1, C8FW, GIG2, TRB1)
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Function
- regulates activation of MAP kinases
- may not display kinase activity
Structure
- belongs to the tribbles family
- contains 1 protein kinase domain
Alternative splicing
named isoforms=1
Expression
- expressed in most human tissues with highest levels in skeletal muscle, thyroid gland, pancreas, peripheral blood leukocytes, bone marrow