Graves disease carrier protein; GDC; Graves disease autoantigen; GDA; mitochondrial solute carrier protein homolog; solute carrier family 25 member 16 (SLC25A1, GDA)

Function

• required for the accumulation of coenzyme A in the mitochondrial matrix

Structure

• belongs to the mitochondrial carrier family
• contains 3 solcar repeats

Compartment

• mitochondrial inner membrane

Pathology

• possible role in Graves disease
• recognized by IgG from patients with active Graves disease

More general terms

• solute carrier family 25 (SLC25, SLC25A)
• mitochondrial protein

Database

• OMIM: https://mirror.omim.org/entry/139080
• UniProt: http://www.uniprot.org/uniprot/P16260.html