B. anthracis edema toxin

Introduction

One of two molecular complexes (edema toxin & lethal toxin) formed from exotoxins of the Bacillus anthracis virulence plasmid pXO1. The complex is formed from edema factor & protective antigen. The complex facilitates entry of the toxin into host cells. The edema factor once intracellular perturbs water homeostasis, via adenylate cyclase activity. Edema toxin inhibits neutrophil function in vitro.

More general terms

• molecular complex
• exotoxin

Additional terms

• B. anthracis lethal toxin
• Bacillus anthracis