therapeutic drug measurement

^[1]^[2]^[3]

Introduction

Measurement of therapeutic drug levels with relatively narrow therapeutic window &/or significant risk of toxicity.

steady-state levels achieved in 4-5 1/2 lives after initiation of therapy or after a dose increase^[3]
see ARUP consult^[1]

↑ ^1.0 ^1.1 ARUP Consult: Drug Testing - Monitoring of Drugs The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/pain-and-addiction-management
ARUP Consult:ARUP Drug Testing (Unexpected Results) Algorithm https://arupconsult.com/algorithm/arup-drug-testing-unexpected-results-algorithm
↑ ARUP Consult: Therapeutic Drug Monitoring - TDM https://arupconsult.com/content/therapeutic-drug-monitoring
↑ ^3.0 ^3.1 NEJM Knowledge+ Psychiatry