signal peptidase complex

Function

• cleaves signal peptides from N-terminus of nascent proteins destined for the secretory pathway after translocation into the lumen of the endoplasmic reticulum

Structure

• complex of five different proteins:
  • SPC25, SPC22/23, SPC21, SPC18, & SPC12

Compartment

• endoplasmic reticulum

More general terms

• molecular complex
• protease; proteinase; endopeptidase