interleukin-5; IL-5; B-cell differentiation factor 1; eosinophil differentiation factor; T-cell replacing factor; TRF (IL5)

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Function

Structure

  • homodimer, disulfide-linked
  • belongs to the IL-5 family

Compartment

secreted

More general terms

Additional terms

References

  1. UniProt http://www.uniprot.org/uniprot/P05113.html
  2. R&D systems' cytokine mini-reviews: IL-5 http://www.rndsystems.com/molecule_detail.aspx?m=1646
  3. Wikipedia; Note: interleukin-5 entry http://en.wikipedia.org/wiki/interleukin_5
  4. SeattleSNPs http://pga.gs.washington.edu/data/il5/
  5. Henderson B & Blake S Therapeutic potential of cytokine manipulation TIPS 13:145 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1589908
  6. Scott P IL-12: initiation cytokine for cell-mediated immunity Science 260:496 1993 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8097337 (secretion)
  7. Milburn et al, A novel dimer configuration revealed by crystal structure at 2.4 A resolution of human interleukin-5. Nature 363:172 1993 (crystal) PMID: https://www.ncbi.nlm.nih.gov/pubmed/8483502

Database