RNA polymerase 2 holoenzyme component SRB7; mediator complex subunit 21; suppressor of RNA polymerase B7 (SRB7, MED21, SURB7)

Function

• component of the mediator complex
• interacts with PPARG (putative)
• interacts with THRA (ligand-dependent)

Structure

belongs to the mediator complex subunit 21 family

Compartment

nucleus (probable)

More general terms

• molecular complex
• nuclear protein

Additional terms

• negative regulator of activated transcription (NAT)
• SRB7 protein

Component of

• mediator complex (mediator of RNA polymerase 2 transcription)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9412
• OMIM: https://mirror.omim.org/entry/603800
• UniProt: http://www.uniprot.org/uniprot/Q13503.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9412