aquaporin-12A; AQP-12 (AQP12A AQP12 AQPX2)

Function

• aquaporins facilitate the transport of water & small neutral solutes across cell membranes (putative)

Structure

• aquaporins contain two tandem repeats each containing 3 membrane-spanning domains & a pore-forming loop with the signature motif Asn-Pro-Ala (NPA)
• belongs to the MIP/aquaporin (TC 1.A.8) family AQP11/AQP12 subfamily

Compartment

membrane (putative)

Expression

restricted to the pancreas

More general terms

• transmembrane 5c protein
• aquaporin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=282680
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=375318
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:375318
• OMIM: https://mirror.omim.org/entry/609789
• UniProt: http://www.uniprot.org/uniprot/Q8IXF9.html