aquaporin-5; AQP-5 (AQP5)
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Function
- forms a water-specific channel
- implicated in the generation of saliva, tears, & pulmonary secretions
Structure
- aquaporins contain two tandem repeats each containing 3 membrane-spanning domains & a pore-forming loop with the signature motif Asn-Pro-Ala (NPA)
- belongs to the MIP/aquaporin (TC 1.A.8) family
Compartment
membrane