lck proto-oncogene
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Introduction
The human lck gene has two distinct promoters giving rise to two distinct transcripts. The type I promoter is that depicted in motif & in the line drawing. The type II promoter contains five start sites but no identified regulatory elements. Increased expression of lck is seen in T-cell leukemias & lymphomas and in colon carcinoma.
More general terms
References
- ↑ Takudua et al Mol Cell Biol 9:2173 1989