annexin A3 (lipocortin-3, placental anticoagulant protein III, PAP-III, 35-alpha calcimedin, inositol 1,2-cyclic phosphate 2-phosphohydrolase PAP-3, ANXA3, ANX3)
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Function
- inhibitor of phospholipase A2
- also possesses anticoagulant properties
- also cleaves cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate
Structure
- a pair of annexin repeats may form one binding site for Ca+2 & phospholipid
- belongs to the annexin family
- contains 4 annexin repeats