dynein light chain 2A (dynein light chain roadblock-type 1, dynein-associated protein Km23, bithoraxoid-like protein, BLP, DNCL2A, DNLC2A, BITH)

Function

• dynein light chain
• may be involved in assembly & motor function of dynein

Structure

belongs to the GAMAD family

Compartment

cytoplasm

Alternative splicing

• named isoforms=2
• additional isoforms seem to exist & may result from the retention of an intron in the cDNA

Expression

• expression in heart, liver, brain & pancreas > placenta, skeletal muscle & kidney > lung, prostate, testis, small intestine & colon

Pathology

• isoform 1 expression is up-regulated in 64% of hepatocellular carcinoma

More general terms

• dynein light chain
• protease inhibitor

Additional terms

• dynein

Database

• OMIM: https://mirror.omim.org/entry/607167
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8365
• UniProt: http://www.uniprot.org/uniprot/Q9NP97.html