serine/threonine/tyrosine-interacting-like protein 1; dual specificity phosphatase inhibitor MK-STYX; dual specificity protein phosphatase 24; Map kinase phosphatase-like protein MK-STYX (STYXL1, DUSP24, MKSTYX)

Function

• probable pseudophosphatase
• contains a Ser instead of a conserved Cys in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase
• the binding pocket may be however sufficiently preserved to bind phosphorylated substrates, & maybe protect them from phosphatases

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class subfamily
• contains 1 rhodanese domain
• contains 1 tyrosine-protein phosphatase domain

Alternative splicing

named isoforms=5

More general terms

• phosphatase inhibitor
• dual specificity phosphatase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51657
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51657
• UniProt: http://www.uniprot.org/uniprot/Q9Y6J8.html