hepatitis B Surface antigen (HBsAg)
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Clinical significance
- component of the outer viral envelope detectable in serum of most patients with acute & chronic hepatitis B infection
- rises with HBeAg, but declines later
- HBsAg indicates HBV infection, acute or chronic
- with development of immunity, HBsAg disappears prior to disappearance of HBcAb IgM
- conversion to HBsAg negative persists long-term in 95%[4]
More general terms
Additional terms
- hepatitis B infection
- hepatitis B surface antigen in serum (HBsAg)
- hepatitis B virus (HBV)
- hepatitis B virus (HBV) serology
Component of
- acellular pertussis vaccine/hepatitis b surface antigen/hepatitis b vaccine/poliovirus vaccine inactivated/tetanus toxoid
- hepatitis serology chronic carrier panel
References
- ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 369
- ↑ Laboratory Medicine: Test Selection & Interpretation. Howanitz & Howanitz (eds), Churchill Livingstone, NY, 1991, pg 818-19
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 14, 18. American College of Physicians, Philadelphia 2006, 2018
- ↑ 4.0 4.1 Alawad AS, Auh S, Suarez D, Ghany MG. Durability of spontaneous and treatment-related loss of hepatitis B s antigen. Clin Gastroenterol Hepatol 2019 Jul 16 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31323381 https://www.cghjournal.org/article/S1542-3565(19)30751-7/pdf