baculovirus protein p35

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Introduction

Baculovirus protein p35 can suppress apoptosis in mammalian cells & may act via inhibition of the ICE-family of cysteine proteinases.

More general terms

References

  1. Kumar S. ICE-like proteases in apoptosis. Trends Biochem Sci. 1995 May;20(5):198-202. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7610484
  2. Bump NJ, Hackett M, Hugunin M, Seshagiri S, Brady K, Chen P, Ferenz C, Franklin S, Ghayur T, Li P, et al. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science. 1995 Sep 29;269(5232):1885-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7569933