dual specificity protein phosphatase CDC14C (CDC14 cell division cycle 14 homolog C, CDC14C, CDC14B2)

Function

• dual-specificity phosphatase
• preferentially dephosphorylates proteins modified by proline-directed kinases

protein tyrosine phosphate + H2O <--> protein tyrosine + phosphate

phosphoprotein + H2O <--> a protein + phosphate

Structure

• composed of two structurally equivalent A & B domains that adopt a dual specificity protein phosphatase (DSP) fold
• belongs to the protein-tyrosine phosphatase family non-receptor class CDC14 subfamily

Compartment

• membrane (putative)
• nucleus, nucleolus
• nucleolar during interphase

More general terms

• phosphoprotein phosphatase
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/A4D256.html