delphilin (glutamate receptor, ionotropic, delta 2-interacting protein 1, GRID2IP)

Function

• postsynaptic scaffolding protein at the parallel fiber- Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton & various signaling molecules
• interacts with C-terminus of the glutamate receptor GRID2 via PDZ domain (putative)

Structure

• contains 1 FH2 (formin homology 2) domain
• contains 2 PDZ domains (DHR domains)

Compartment

cell junction, synapse (putative)

More general terms

• receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6419
• UniProt: http://www.uniprot.org/uniprot/A4D2P6.html