Xenotropic & polytropic retrovirus receptor 1 (protein SYG1 homolog, Xenotropic & polytropic murine leukemia virus receptor X3, X-receptor, XPR1, SYG1, XR)

Function

• may function in G-protein coupled signal transduction (putative)
• putative receptor for xenotropic & polytropic murine leukemia retroviruses

Structure

• belongs to the SYG1 family
• contains 1 SPX domain

Compartment

cell membrane

Alternative splicing

named isoforms=2

Expression

• widely expressed
• detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas & skeletal muscle
• expressed in fetal liver

Notes

• unclear whether its ability to act as a receptor for xenotropic & polytropic murine leukemia retroviruses is relevant in vivo & whether such viruses can infect human

More general terms

• phosphoprotein
• receptor
• transmembrane 8 protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9213
• OMIM: https://mirror.omim.org/entry/605237
• UniProt: http://www.uniprot.org/uniprot/Q9UBH6.html